Early ovarian cancer surgical staging important clinical value

A scholar from the Netherlands led multinational collaborative research suggest that the early epithelial ovarian cancer surgical staging, can predict whether the patients have residual ovarian cancer and the need for postoperative adjuvant chemotherapy.

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Diagnosed with ovarian cancer diagnosis

Ovarian cancer early detection, early treatment, the greater the chance of cure. But ovarian cancer early detection more difficult. Usually, women with ovarian cancer no symptoms or mild discomfort, only to the late period before a noticeable symptoms. Scientists are studying the symptoms, identify methods of ovarian cancer. They found blood in the CA-125, a tumor marker in women with ovarian cancer was significantly increased; Ultrasound can also help early detection of diseases.
The census is a large-scale tumors, including prostate, lung, colorectal and ovarian cancer, the evaluation of tumor markers in the blood of the level of CA-125 and transvaginal ultrasound examination in the early diagnosis of ovarian cancer value.

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Ovarian cancer knowledge

Basic symptoms: early ovarian cancer usually no obvious symptoms, if there is non-specific symptoms, such as menstrual disorder, mild gastrointestinal discomfort. With the growth of tumors may arise under bloating, discomfort, or sometimes because of oppression involved in the bladder or rectum and frequency, diarrhea, constipation,. More advanced symptoms from ascites, omental or metastatic gastrointestinal such as abdominal distension, shortness of breath, abdominal discomfort, and incomplete intestinal obstruction or even obstructive symptoms. Part of mesenchymal tumors or tumor invasion of genistein and uterus can cause irregular vaginal bleeding. If a tumor metastasis may have different performance of the corresponding organ involvement.

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Cytoreductive surgery in the treatment of ovarian cancer Comprehensive Application and prospects

Cytoreductive surgery in the treatment of ovarian cancer Comprehensive Application and prospects

Foreign Medical Obstetrics and Gynecology volumes in 1999 Vol 26 No. 2

Tianjin Medical University General Hospital of Obstetrics and Gynecology (300,052) of the new QU (Summary) if Mi (revision)

Abstract <BR> since the 1980s, complete cytoreductive surgery to cisplatin-based combination chemotherapy for ovarian cancer as a conventional model, cytoreductive surgery is the complete impact of the prognosis of patients with one of the important factors for recurrent ovarian cancer once again cytoreductive surgery still some value , but to improve the survival rate of patients is more important to be effective after chemotherapy treatment as a necessary complement. Early ovarian cancer retroperitoneal lymph node dissection is reasonable and significance of the still controversial.

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Ovarian cancer outlined

[Summary]

Ovarian cancer is a common cancer of female genital mutilation one of the incidence of cervical cancer and after cancer of the uterus, which ranked third. But ovarian cancer death, accounts of the first gynecologic tumors, right pose a serious threat to women's lives. Because ovarian embryonic development, organization anatomy and endocrine function more complicated, it may be suffering from benign tumors or malignant. Because of early ovarian cancer in asymptomatic, and the identification of its type benign and malignant very difficult, ovarian carcinoma laparotomy in ovarian tumor confined to only 30%, most have spread to the uterus, bilateral annex, the omentum and pelvic organs, both in the diagnosis of ovarian cancer and governance the treatment is a major problem indeed. Over the years experts on the pathological form of ovarian cancer, the development of clinical and treatment programs for many of accumulated a lot of experience, so far, statistics on domestic and foreign clinical data, the five-year survival rate of only 25% to 30%.

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Conventional treatment

The choice of ovarian cancer surgery, chemotherapy and radiotherapy. But because of its pathological type complex, qualitative, without a diagnosis and staging laparoscopy or laparotomy, it is difficult clear. In addition to surgery is not generally the case or have the type of tumor in patients with systemic conditions not competent to surgery, chemotherapy or radiotherapy to trial again after surgery to consider, as appropriate, generally the preferred treatment. Surgical exploration can be further defined tumor types and scope of involvement, clear staging, not only for postoperative chemotherapy and radiotherapy provide basis, and possible removal of the tumor, chemotherapy or postoperative radiotherapy or create conditions to improve efficacy.

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Fallopian tube cancer

Primary tubal cancer is scarce. This cancer patients, the average age is 50 to 60 years old. Risk factors not yet well defined, however, chronic salpingitis or other inflammatory diseases (such as tuberculosis) may cause. Patients can have a long history of infertility.

Over 95% of the fallopian tube cancer is papillary serous adenocarcinomas; The minority is sarcoma. Its diffusion and similar ovarian cancer, tubal carcinoma can be directly extended disseminated, or through lymphatic vessels. With ovarian cancer staging similar symptoms, signs and diagnosis

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Ovarian cancer clinical manifestations and treatment

Clinical manifestations

(1) a <BR> symptoms, age occurred in perimenopausal women. Over more than 35 years of epithelial ovarian cancer, while those below the age of 35 occurred reproductive cell malignancies.
2, the pain may be due to malignant ovarian tumor of the changes, such as hemorrhage, necrosis, the rapid growth caused a considerable degree of persistent pain. The inspection found a local tenderness.
3, Irregular Menstruation see irregular bleeding, bleeding after menopause.
4, weight loss was sexually advanced thin.

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Model Diagnosis

The cytological diagnosis of ovarian cancer cells, including shedding diagnosis and fine-needle aspiration cytology diagnosis learned of two parts. Check for gynecologic cytology clinical has for decades. Fine needle aspiration cytology lessons, the past 20 years in various tumor diagnosis has been widely used, this method of diagnosis of ovarian tumors of some value, advanced or recurrent tumors and lymph node metastases diagnosis, not only diagnosis, but also avoid some unnecessary laparotomy.

One, cytological diagnosis

(1) cytology examination: exfoliated cells can be obtained specimens from three aspects, including: ① vaginal, cervical and uterine tube; ② ascites or peritoneal fluid; ③ rectal deciduous uterine puncture lessons.

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Diagnostic Classification

Surgery

According to a medical examination and transvaginal ultrasound findings suspected ovarian cancer is often a laparotomy to be confirmed histology, and tumor stage and tumor debulking surgery. Histological need to be certified to remove ovarian cysts Mixed other causes, including non - epithelial ovarian cancer (such as interstitial or germ cell tumors), other primary site of tumor metastasis to the ovary (such as the adhesion of), or benign lesions, such as endometriosis. The adhesion is usually of signet ring cell tumor, representatives from primary adenocarcinoma of the stomach metastatic ovarian cancer. However, other parts of the original cancer, such as colon, appendix, the gallbladder and breast (special lobular invasive carcinoma) will also transfer to ovarian. At laparotomy surgery during the stage, right after the decision-making guidance provided important information, especially for patients with early (discussed below). Finally, the tumor debulking surgery (initial cytoreductive surgery) is the first of an important part of the operation because of residual tumor with a diameter of less than 1 cm larger than the residual tumor with a high survival rate.

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