OVARIAN CANCER

A new study shows that moderate physical exercise may help women reduce the risk of ovarian cancer. The study was supported by a healthy lifestyle can prevent women tumor development of this theory.

Public Health Agency of Canada study on 442 women with ovarian cancer and did not have ovarian cancer, the situation is similar 2,135 women conducted a questionnaire of the survey. According to the survey findings, which sports the highest levels of women, the risk of suffering from ovarian cancer has been noticeably reduced. Regular exercise the highest level of women suffering from ovarian cancer risk reduction of 33%; The level of the highest female, the <BR> risk reduction of 27%.

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For what age women should be preventive ovariectomy, between different gynecological physician there is a considerable difference. Jacobs Oram and the Royal College of Obstetrics and Gynecology doctors on preventive attitude ovariectomized done a survey, the results showed that: only 2% to gynecologists for women aged 40 to 44 the ovary; 20% of doctors agreed with 45 to 49-year-old women's ovary; 51% think Resectability aged over 49-year-old women's ovary; 85% agree that postmenopausal women with ovarian. Alaska gynecologists, 35% agree with women aged 40 to 44 the ovary; 81% agree with women aged 45 to 49 the ovary; 95% agree with women over the age of 49, the ovary.
Some of the literature suggested that the age for women aged ≥ 40 ovariectomized preventive purposes. However, while some other articles that only deal with ≥ 45 years of age patients with preventive ovariectomy. It is clear that the majority of women with ovarian also not aware of estrogen replacement therapy (estrogen replacement therapy, ERT) the importance, from the reported in the literature it is not difficult to see that the compliance ERT not ideal, however, the role of estrogen loss is real. After ovariectomy, the ERT begin compliance was 31% to 89%; The long-term application, a decrease of 13% to 51%. Under existing ERT compliance of the relevant information can be estimated preventive ovariectomized will lead to the age of 45 or more young women to shorten life expectancy. For example, a 35-year-old women, in preventive ovary after, if they failed to ERT, then her life expectancy will decrease 1.4 years. Siddle, proved to hysterectomy for women, ovarian failure will be the age of natural menopause, as early as four years (45.4? ? .0 49.5-right? ? .04), And 34% of women in the two years after emerging ovarian failure and menopause symptoms .
Thus, clinicians must be aware of ovarian hysterectomy after reservation for women should be ahead of ERT treatment.

Tags: age, early, eat, ert, estrogen, gynecological, head, life, ovarian, ovary, patients, preventive, symptoms, therapy, treatment, women

Most of the malignant ovarian tumors, radiation therapy for various effects are poor. Therefore, in the treatment of malignant ovarian tumor was not first consider radiotherapy. After laparotomy confirmed to be malignant ovarian tumor resection not all, in vitro viable X-ray irradiation. But many of ascites are not OK radiotherapy; The abdominal tumor metastasis to the effect of not limited to those within the pelvic cavity. X-ray irradiation is also used in vitro malignant ovarian tumor before and after surgery. Preoperative radiotherapy for patients with radiation therapy after the word four to six weeks should surgery again night, while radiation caused by adhesions, surgery often caused difficulties. Surgery will be in regular radiation treatment after two weeks before and after the start, such as whole body ill patients should first correct.
(1), abdominal irradiation radiation field including full pots of abdominal viscera, or by Ono divided into two to four vertical irradiation of Ono, tumor dose of 25 Gy ~ / 6 to 8 weeks. General liver, kidney tolerance were 30 Gy and 18 Gy, such as the super-dose, should shielding protection. Whole abdominal irradiation after Ono, the largest general tolerance of 30 Gy / 6 to 7 weeks. This dose is not LD50 of ovarian cancer, while Ono irradiation reaction, difficult patient tolerance. Delcios in 1963, a fully mobile strip abdominal irradiation in the treatment of ovarian cancer. Each abdominal irradiation of 10 cm, radiation field from the upward movement in the entire basin to include abdominal, each irradiation in 12 days. Tumor radiation dose of 26 to 28 Gy. The biological effects of radiation and improve the patient's response to radiotherapy.
(2), pelvic tumor irradiation dose of 40 to 60 Gy, 6 to 8 weeks to complete.
(3), plus whole abdominal pelvic irradiation Ono whole abdominal irradiation may be, or transfer surgery strip irradiation dose with the former. Pelvic organ tolerance, to improve efficacy, and pelvic irradiation dose of 20 to 30 Gy, ovarian cancer is the commonly used method.
(4), abdominal radionuclide therapy for patients early preventive treatment, and only a small residual tumor after treatment. Surgery not cut net of malignant ovarian tumor metastases can be injected with the radioactive colloid 98 or 32 P, or diluted with saline injected into the abdominal cavity to prevent cancer formation of ascites, malignant ovarian cancer has been with ascites, the catheter may produce ascites part, to be injected colloidal gold 98 or 32 P . It should be noted 98 of the radioactive colloid and 32 P for intraperitoneal injection, also caused radioactive hepatitis possible, it should be repeated in application check liver function for timely processing.

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Despite preventive ovariectomy in the prevention of high-risk patients with ovarian cancer in a certain role, but still cautious, because ovarian cancer and distinguish the cavity cancer can occur. In one study, 16 of 28 high-risk family members to preventive ovariectomized later, three occurred, and diffuse abdominal cancer. These high-risk patients, and that the author: genetic susceptibility not only confined to the ovary, but also extends to occur in embryos with ovarian related organizations. Formerly, reported preventive nest after resection of 324 cases of women, six cases (1.8%) of the peritoneum of the original tumor. Therefore, the preventive after resection of primary ovarian peritoneal tumor, and less common, the incidence rate of about 2%.

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Disease Overview

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Epithelial ovarian cancer in the United States is a relatively rare in Gynecologic Oncology, 2004, there were approximately 25,580 cases of new onset patients, 16,090 cases patients died. The majority of patients with advanced cancer, treatment for surgical resection and postoperative to platinum-based chemotherapy. During the past 10 years, chemotherapy improved survival rates improve, and recurrent tumor treatment more effective. In addition, the genetic risk factors for making in-depth understanding of the prevention strategy to become individualized approach to bilateral tubal women - ovarian surgery. This report summarized the clinical characteristics of epithelial ovarian, after reports focus on the treatment of the latest developments.

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Swedish experts recently warned that, for those with breast or ovarian cancer family history of the young women, if they have been diagnosed with breast cancer, then their risk of ovarian cancer risk would be significantly increased by 10 times. So even the experts recommended that certain breast cancer patients may be necessary for the prevention of suffering from such as ovarian cancer
Preventive measures. Kjell Bergfeldt Karolinska Institute, Doctor of Medicine, in its study of more than 30,000 cases compared 70 patients with breast cancer under the age of the medical records, and also whether their immediate family members with breast cancer or ovarian cancer cases were investigated. The results showed that if their mothers, sisters or daughters of people with breast cancer or ovarian cancer, who before the age of 40 was diagnosed with breast cancer before the age of 70 women with ovarian cancer risk will increase six-fold and 17-fold. Relevant experts believe that the discovery confirmed the existence of two types of cancer among some related links. Previous studies have already noted, carrying the BRCA1 or BRCA2 gene mutations in breast cancer patients with about 40% of people will be suffering from ovarian cancer.

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Kikuchi, the Japanese report, have received platinum multidrug chemotherapy for recurrent ovarian cancer Japanese women, a weekly carboplatin and paclitaxel chemotherapy in a meeting, can significantly prolong survival, and patients can be tolerated. (Int J Cancer YORK 2005,15:45)

The case control study included surgery and platinum-based adjuvant chemotherapy complete remission for at least 6 months after the recurrence of ovarian cancer patients. Of the 68 patients, 27 patients received a weekly meeting of Taxol and carboplatin chemotherapy (WTJ) (Group I), carboplatin (AUC area under the curve for 2) plus paclitaxel (80 mg/m2); The remaining 41 patients (Group II) to platinum-based (P ) other chemotherapy, 37 patients with CAP program, a monthly meeting of carboplatin and paclitaxel program four cases.

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Speaking at the main address on the prevention of epithelial ovarian tumors.

※ never taken oral contraceptives and contraceptive for women, compared to more than five years if the pill can reduce the risk of 60%.
* Encourage breastfeeding, extended breastfeeding time.
* Diet: eat more fruits and vegetables, recruits had long before learned high-fat foods, especially animal fat.
* The right of a family history of ovarian cancer prevention guide women: in genetic counseling and genetic determination.
* Preventive ovariectomized: over the age of 40 have a family history of ovarian cancer patients, and sometimes may recommend surgical excision of ovarian his deeds.
* Tubal ligation or hysterectomy: Generally speaking, these operations only in a suitable medical reasons before implementation, and not only for the prevention of the occurrence of ovarian cancer

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Although ovarian cancer chemotherapy drug developed considerable progress has been made, but patients with ovarian cancer and the overall survival rate has not improved markedly. Philadelphia's Fox Chase Hospital Dr. Bernard of ovarian cancer screening, treatment and prevention of, and possible future trends.

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