OVARIAN CANCER

(1) of ovarian cancer there are three types of pathology

① primary cancers: Primary ovarian in itself, is generally solid, tumor size, a sustained round, smooth surface, may have nodules processes. Biopsy showed gray ash or red, hard soft different microscope showed various types, such as adenocarcinoma, medullary carcinoma. The beginning is often unilateral, often late into bilateral, the other side of ovarian cancer may be primary, or it may be transferred from the contralateral.

② secondary cancer: from ovarian or other cystadenoma from malignant ovarian tumor.

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Serous cystadenoma
Zhu serous tumor of the kidney from the body cavity epithelium, is the most common tumors of the ovary. According to national statistics, the total of 2007-09-07 16:00:00.1% of ovarian tumors common in women aged 30-40. The unilateral nature, but there are also many of the bilateral. Simple solution can be divided into gland capsule and two papillary serous cystadenoma.

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Patients with malignant ovarian tumor when treatment is late (> Phase II), ovarian cancer is the surgical treatment called tumor or cytoreductive surgery or large resection.
Surgery is to do everything possible to the original tumor resection and can see the pots, peritoneal metastasis, so that each region of residual lesion diameter of less than 2.0 cm to 1.5 cm. Intraoperative from ascites fluid or cells for blood screening. Because ovarian and uterine cancer often, the annex or visco-invasion, peritoneal and keep pots, it is more of "carpet-volume" or "dumplings", from extraperitoneal space elements from the peritoneal wall, bladder and pelvic floor serous peritoneal, along with the uterus and pelvic peritoneum block tumor resection. The pots have peritoneal metastasis tissues or organs should be possible to complete resection or partial resection, resection of the omentum, some intestinal resection, resection of the bladder or ureter shifting values. The removal of the tumor as possible aim is to enhance postoperative radiotherapy and chemotherapy effect. The merger of ovarian cancer ascites, regardless of whether all resection are advised to intraperitoneal indwelling catheter for intraperitoneal injection of anti-cancer drugs. Anti-cancer drugs or radioisotopes for preparation also can be injected directly unresectable tumors.
Surgery can not decide in its benign and malignant ovarian tumor resection specimens should be admitted or contralateral ovarian tissue frozen tablets sent for histopathologic examination. There is no such conditions, generally after the contralateral normal ovarian As can be temporarily retained, pathological specimens were sent checks to clear in nature, and close observation. The previous suspected metastatic ovarian tumor and failed to find its source, should be in operation in detail in the original exploration of abdominal lesions, after further treatment for reference.

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Disease Overview

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Basic symptoms: early ovarian cancer usually no obvious symptoms, if there is non-specific symptoms, such as menstrual disorder, mild gastrointestinal discomfort. With the growth of tumors may arise under bloating, discomfort, or sometimes because of oppression involved in the bladder or rectum and frequency, diarrhea, constipation,. More advanced symptoms from ascites, omental or metastatic gastrointestinal such as abdominal distension, shortness of breath, abdominal discomfort, and incomplete intestinal obstruction or even obstructive symptoms. Part of mesenchymal tumors or tumor invasion of genistein and uterus can cause irregular vaginal bleeding. If a tumor metastasis may have different performance of the corresponding organ involvement.

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Cytoreductive surgery in the treatment of ovarian cancer Comprehensive Application and prospects

Foreign Medical Obstetrics and Gynecology volumes in 1999 Vol 26 No. 2

Tianjin Medical University General Hospital of Obstetrics and Gynecology (300,052) of the new QU (Summary) if Mi (revision)

Abstract <BR> since the 1980s, complete cytoreductive surgery to cisplatin-based combination chemotherapy for ovarian cancer as a conventional model, cytoreductive surgery is the complete impact of the prognosis of patients with one of the important factors for recurrent ovarian cancer once again cytoreductive surgery still some value , but to improve the survival rate of patients is more important to be effective after chemotherapy treatment as a necessary complement. Early ovarian cancer retroperitoneal lymph node dissection is reasonable and significance of the still controversial.

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Early ovarian cancer usually no obvious symptoms, if there is non-specific symptoms, such as menstrual disorder, mild gastrointestinal discomfort. With the growth of tumors may arise under bloating, discomfort, or sometimes because of oppression involved in the bladder or rectum and frequency, diarrhea, constipation,. More advanced symptoms from ascites, omental or metastatic gastrointestinal such as abdominal distension, shortness of breath, abdominal discomfort, and incomplete intestinal obstruction or even obstructive symptoms.

Part of mesenchymal tumors or tumor invasion of genistein and uterus can cause irregular vaginal bleeding. If a tumor metastasis may have different performance of the corresponding organ involvement.

Tags: abdominal, bleeding, cancer, cause, cyst, cystic, early, eat, growth, mass, metastasis, metastatic, oppression, ovarian, pelvic, symptoms, time, tumor, tumors, usually

Ovarian cancer is common gynecologic cancer, female genital tumors about 1 / 3. Can occur at any age, and women with reproductive seen. The incidence of ovarian cancer is women's genital cancer Habitat third place, as early diagnosis difficult, often found at the already advanced, but the mortality rate for the first gynecologic malignancies.
[Diagnosis]

A Symptoms

(1) abdominal discomfort or medium sized benign tumor rapid growth often cause bloating and discomfort.

(2) abdominal mass benign swelling growth slow, difficult to be discovered, patients are often inadvertently touched. Malignant tumors grow fast, easily detected.

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Because some patients with abdominal mass for the first symptom, the disease easily confused with primary ovarian cancer. While most patients with muscle. Therefore, the CT-assisted examination found pelvic masses accurate diagnosis difficult and the nature of its sources. Shoji Kamiura reported in 64 patients, only 50% of patients (19/38) in the initial treatment has been confirmed by histopathology metastatic ovarian cancer, and in these 19 patients, only 37% (7 / 19) in the preoperative diagnosis, and the rest 63% (12/19) is OK pathological examination after diagnosis.
In recent years, CEA monoclonal antibody research in the identification of primary and metastatic ovarian cancer provided some evidence. But CEA in primary ovarian cancer in a certain expression.且CEA种类繁多，因此需要找到一个有效的CEA单克隆抗体来鉴别原发灶或转移性卵巢癌，CA125为卵巢癌单抗，在浆液性卵巢癌中表达率最高，而在粘液性卵巢癌中阴性，故CA125在鉴别诊断中有一定限制。 Thomas Rutherford, reported that their research shows that in metastatic ovarian cancer, the lack of ER - β expression. China's Fudan University, Shanghai Medical College Cancer Hospital study found: cytokeratin 7 monoclonal antibodies in the primary ovarian carcinoma in pursuing expression in gastrointestinal adenocarcinoma sources of generally negative.

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Surgery

According to a medical examination and transvaginal ultrasound findings suspected ovarian cancer is often a laparotomy to be confirmed histology, and tumor stage and tumor debulking surgery. Histological need to be certified to remove ovarian cysts Mixed other causes, including non - epithelial ovarian cancer (such as interstitial or germ cell tumors), other primary site of tumor metastasis to the ovary (such as the adhesion of), or benign lesions, such as endometriosis. The adhesion is usually of signet ring cell tumor, representatives from primary adenocarcinoma of the stomach metastatic ovarian cancer. However, other parts of the original cancer, such as colon, appendix, the gallbladder and breast (special lobular invasive carcinoma) will also transfer to ovarian. At laparotomy surgery during the stage, right after the decision-making guidance provided important information, especially for patients with early (discussed below). Finally, the tumor debulking surgery (initial cytoreductive surgery) is the first of an important part of the operation because of residual tumor with a diameter of less than 1 cm larger than the residual tumor with a high survival rate.

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