OVARIAN CANCER

(1), ovarian cancer-chemotherapy drug commonly used drug <BR> melphalan (PAM) 0.2 ^ / ㎏ d, oral, 4 ~ for a course on the 5th, rest four to six weeks after duplication. Thiotepa (161-169) 10 ^ / times, intramuscular or intravenous injection, used five times, every other day to once a total of 300 ~ 500 days for an induction course. 6 to 8 weeks under the condition repeat. Cyclophosphamide (CTX) 50 ~ 100 ^ / day, oral, 7 ~ 10 Tianyi treatment, two weeks after duplication. Or 400 ^ / day, intravenous, oral to four days. Adriamycin (ADM) 50 ~ 70 ^ / ㎡, intravenous injection. Every three weeks.
(2), and malignant ovarian tumor joint chemical treatment of ovarian cancer chemotherapy are better response. In recent years the chemical treatment of tumors faster progress in the treatment of ovarian cancer Habitat has an important place to improve the treatment of ovarian cancer play a positive role as a surgical adjuvant therapy, commonly used in the preoperative, intraoperative and postoperative, but often require a longer period of intermittent medication, and the human body toxicity also sometimes larger. In most cases, it is difficult to ovarian cancer surgery primary tumor and metastasis consider chemical treatment based treatment.

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Disseminated and metastasis 1. Transfer of malignant ovarian tumor growth and metastasis, and other parts of the same direct spread of cancer, and the lymphatic and blood way. But the transfer spread mainly by direct more directly transferred to pots, abdominal organs and organizations, or transfer of Tai omentum, mesenteric, in a number of intraperitoneal nodular mass, a certain degree of mobility; Peritoneal or transferred to the pelvic floor in the vaginal fornix after palpation, palpable in the womb may have rectal Waterloo a papillary protrusions, even penetrating pelvic viscera, a sinus, and the rectum,; a vaginal or urethral cancer tissue from the pus and bleeding. Ovarian cancer found in the lymph node metastasis rate as high as 50%, or even transferred to the left supraclavicular lymph nodes, or perineum, is in the diagnosis and treatment of ovarian cancer, attention. 2. Common vicious invasion on the side of the fixed pelvic advanced malignant ovarian tumors, resulting in partial perivascular infiltration oppression, to the side of lower extremity venous disruption, edema formation. If the intestine of oppression by the vicious invasion, caused obstruction symptoms; Ureteral pressure, often the hydronephrosis. Phase I clinical Asia ovarian cancer metastasis Positions The number of cases Transfer rate (%)

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Most of the malignant ovarian tumors, radiation therapy for various effects are poor. Therefore, in the treatment of malignant ovarian tumor was not first consider radiotherapy. After laparotomy confirmed to be malignant ovarian tumor resection not all, in vitro viable X-ray irradiation. But many of ascites are not OK radiotherapy; The abdominal tumor metastasis to the effect of not limited to those within the pelvic cavity. X-ray irradiation is also used in vitro malignant ovarian tumor before and after surgery. Preoperative radiotherapy for patients with radiation therapy after the word four to six weeks should surgery again night, while radiation caused by adhesions, surgery often caused difficulties. Surgery will be in regular radiation treatment after two weeks before and after the start, such as whole body ill patients should first correct.
(1), abdominal irradiation radiation field including full pots of abdominal viscera, or by Ono divided into two to four vertical irradiation of Ono, tumor dose of 25 Gy ~ / 6 to 8 weeks. General liver, kidney tolerance were 30 Gy and 18 Gy, such as the super-dose, should shielding protection. Whole abdominal irradiation after Ono, the largest general tolerance of 30 Gy / 6 to 7 weeks. This dose is not LD50 of ovarian cancer, while Ono irradiation reaction, difficult patient tolerance. Delcios in 1963, a fully mobile strip abdominal irradiation in the treatment of ovarian cancer. Each abdominal irradiation of 10 cm, radiation field from the upward movement in the entire basin to include abdominal, each irradiation in 12 days. Tumor radiation dose of 26 to 28 Gy. The biological effects of radiation and improve the patient's response to radiotherapy.
(2), pelvic tumor irradiation dose of 40 to 60 Gy, 6 to 8 weeks to complete.
(3), plus whole abdominal pelvic irradiation Ono whole abdominal irradiation may be, or transfer surgery strip irradiation dose with the former. Pelvic organ tolerance, to improve efficacy, and pelvic irradiation dose of 20 to 30 Gy, ovarian cancer is the commonly used method.
(4), abdominal radionuclide therapy for patients early preventive treatment, and only a small residual tumor after treatment. Surgery not cut net of malignant ovarian tumor metastases can be injected with the radioactive colloid 98 or 32 P, or diluted with saline injected into the abdominal cavity to prevent cancer formation of ascites, malignant ovarian cancer has been with ascites, the catheter may produce ascites part, to be injected colloidal gold 98 or 32 P . It should be noted 98 of the radioactive colloid and 32 P for intraperitoneal injection, also caused radioactive hepatitis possible, it should be repeated in application check liver function for timely processing.

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Denmark Gronloud such report, as paclitaxel plus platinum chemotherapy after complete remission in patients with ovarian cancer, if recurrence of a solitary lesion again cytoreductive surgery may improve survival. (Eur J Surg Oncol 2005,31:67)

In the retrospective study selected criteria: 1 Guide to the residual initial stage operation and confirmed by histological examination of epithelial ovarian cancer; (2) complete remission after first-line treatment; 3. Imaging confirmed pots peritoneal metastasis; (4) Surgical resection of lesions for the purpose.

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In recent decades, the treatment of gynecologic cancer progress has been made, but only the ovarian cancer there is no significant improvement. The incidence of ovarian cancer Habitat Gynecologic Oncology third, but it was the first fatality rate. Its cause high mortality due to the growth of ovarian cancer site concealment, not be seen directly, patients still in the early stages of the lack of simple and practical method of diagnosis. Most (about 70%) have been newly diagnosed patients with peritoneal metastasis pots. Currently taken by surgery, radiotherapy, chemotherapy and immunotherapy for the treatment of Chinese medicine integrated with the right therapy, in the treatment of advanced worse still, it is difficult to avoid recurrence. But by early diagnosis and treatment of patients with ovarian cancer prognosis is quite different. Case in epithelial ovarian cancer, according to statistics, the five-year survival rate, 80% for stage I, 40% for Stage II; While Ⅲ period just below 5%. Visibility early detection, early diagnosis and treatment of patients with ovarian cancer is a lifetime event.

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(1) of ovarian cancer there are three types of pathology

① primary cancers: Primary ovarian in itself, is generally solid, tumor size, a sustained round, smooth surface, may have nodules processes. Biopsy showed gray ash or red, hard soft different microscope showed various types, such as adenocarcinoma, medullary carcinoma. The beginning is often unilateral, often late into bilateral, the other side of ovarian cancer may be primary, or it may be transferred from the contralateral.

② secondary cancer: from ovarian or other cystadenoma from malignant ovarian tumor.

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Serous cystadenoma
Zhu serous tumor of the kidney from the body cavity epithelium, is the most common tumors of the ovary. According to national statistics, the total of 2007-09-07 16:00:00.1% of ovarian tumors common in women aged 30-40. The unilateral nature, but there are also many of the bilateral. Simple solution can be divided into gland capsule and two papillary serous cystadenoma.

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Patients with malignant ovarian tumor when treatment is late (> Phase II), ovarian cancer is the surgical treatment called tumor or cytoreductive surgery or large resection.
Surgery is to do everything possible to the original tumor resection and can see the pots, peritoneal metastasis, so that each region of residual lesion diameter of less than 2.0 cm to 1.5 cm. Intraoperative from ascites fluid or cells for blood screening. Because ovarian and uterine cancer often, the annex or visco-invasion, peritoneal and keep pots, it is more of "carpet-volume" or "dumplings", from extraperitoneal space elements from the peritoneal wall, bladder and pelvic floor serous peritoneal, along with the uterus and pelvic peritoneum block tumor resection. The pots have peritoneal metastasis tissues or organs should be possible to complete resection or partial resection, resection of the omentum, some intestinal resection, resection of the bladder or ureter shifting values. The removal of the tumor as possible aim is to enhance postoperative radiotherapy and chemotherapy effect. The merger of ovarian cancer ascites, regardless of whether all resection are advised to intraperitoneal indwelling catheter for intraperitoneal injection of anti-cancer drugs. Anti-cancer drugs or radioisotopes for preparation also can be injected directly unresectable tumors.
Surgery can not decide in its benign and malignant ovarian tumor resection specimens should be admitted or contralateral ovarian tissue frozen tablets sent for histopathologic examination. There is no such conditions, generally after the contralateral normal ovarian As can be temporarily retained, pathological specimens were sent checks to clear in nature, and close observation. The previous suspected metastatic ovarian tumor and failed to find its source, should be in operation in detail in the original exploration of abdominal lesions, after further treatment for reference.

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You are interested in the manual open to learning the prevention and treatment of ovarian cancer, you may answer the following questions, which are from the United States, 199 by the latest knowledge of ovarian cancer questionnaire. Facts have proved that the developed countries in Europe and the United States these people are aware of ovarian cancer rarely. Gynecologic Oncology experts say: lack of knowledge of ovarian cancer is the cause of ovarian cancer mortality leapt to the forefront of gynecologic cancer mortality one of the major reasons. How do you these basic knowledge of the number of ovarian cancer?

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Basic symptoms: early ovarian cancer usually no obvious symptoms, if there is non-specific symptoms, such as menstrual disorder, mild gastrointestinal discomfort. With the growth of tumors may arise under bloating, discomfort, or sometimes because of oppression involved in the bladder or rectum and frequency, diarrhea, constipation,. More advanced symptoms from ascites, omental or metastatic gastrointestinal such as abdominal distension, shortness of breath, abdominal discomfort, and incomplete intestinal obstruction or even obstructive symptoms. Part of mesenchymal tumors or tumor invasion of genistein and uterus can cause irregular vaginal bleeding. If a tumor metastasis may have different performance of the corresponding organ involvement.

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