Recurrent ovarian cancer chemotherapy new method - conventional chemotherapy drug efficacy forecast molecular targeted chemotherapy

Ovarian cancer is the worst prognosis of gynecologic tumors. Patients with advanced epithelial ovarian cancer five-year survival rates generally below 30%, mainly in patients with relapsing most (about 75%), relapse after chemotherapy to poor results.

For the treatment of recurrent ovarian cancer chemotherapy drugs many, no less than 10 species, but only clinical remission rate of 20% to 30%, no progress median survival time (PFS) for 2 to 6 months, the median overall survival (OS) for six to 12 months. Therefore, to improve the efficacy of chemotherapy drugs delay, but the development of new drugs is very difficult, efficient use of existing drugs is an effective way to <BR>.

Tags: cancer, cases, chemotherapy, cisplatin, clinical, drug, drugs, early, eat, exploration, gene, group, method, ovarian, p53, paclitaxel, patients, pmtc, poor, positive, prognosis, rate, second, study, survival, taxol, therapy, time, treatment, tumor, tumors

Ovarian cancer rehabilitation period Conditioning

(1) life Conditioning
1, the personal attention sometimes, suitable living environment, adequate exercise, not overstrain. Particularly in long-term therapy, should rest, and maintain physical strength, should be nutrient-rich diet, with attention to the change in the weather changes clothes to avoid bacteria, viruses and other infections.
2, the appropriate useful life of physical and mental health, excessive, harmful to patients. However, during chemotherapy after surgery and not sex life, to question the basic physical state after the resumption before the beginning. Terminally ill patients should avoid sexual life.
(2) diet conditioning
Ovarian cancer eating conditioning is very important. After surgical treatment, clinical seen qi deficiency, spleen and stomach slump, the existing lack of nutrients, organisms dysfunction. Thus in modulating diet, we should pay attention to proper nutritional supplements, heat, to the high-protein, high-vitamin food, but also conditioning the spleen and stomach function, exciting Wei Qi, restore chemical gas source, acquired strengthening of the party. In addition to food choices milk, eggs, the average patient to eat more fresh vegetables, fruits, protein and various vitamins, blah mother pork. Ovarian tumors after serving more attention should still Tiaojing body, nourishing the liver and kidney of goods, such as pomegranates, Mangosteen, loquat fruit, fig, banana, lemon, Longan, grapes, walnuts, mulberry, black sesame, watermelons, Melon, black fungus, watery gruel, yam flour, Lotus, chestnut, mung bean, Chinese prickly ash, placenta, carp, crucian carp, eggs, milk and so on. Diet also used conditioning.
(3) psychotropic
Maintain a healthy psychological state and optimistic mood is conducive to the normal endocrine regulatory activities, which will help enhance ovarian cancer effect. Practice has proved that where the spirit of optimism and confidence than adequate treatment, and doctors with better efficacy patients better, otherwise poor. Correct pessimism, negative psychological state and inspire incentive to overcome disease patients establish the confidence to achieve good results.

Tags: age, body, cancer, chemotherapy, clinical, confidence, diet, eat, eggs, life, ovarian, patients, physical, poor, protein, psychological, surgery, surgical, therapy, time, treatment, tumor, tumors

Treatment of ovarian cancer chemotherapy new program

Researchers reported that the joint use of both cisplatin and paclitaxel chemotherapy drug for ovarian cancer achieved better clinical remission rate and a higher survival rate, this new program has become advanced ovarian cancer patients with standard treatment programs.

From the European Organization for Cancer Research and Treatment of Dr Piccart, a group of researchers across the Atlantic to the two large-scale clinical trials group that cisplatin and paclitaxel (TP) both chemotherapy treatment of advanced ovarian cancer with significant advantages.

Tags: age, anti, cancer, chemotherapy, cisplatin, clinical, drug, eat, grams, group, history, ovarian, paclitaxel, patients, rate, study, survival, therapy, treatment, tumor, tumors

Intraperitoneal chemotherapy should be first-line therapy in ovarian cancer

A large number of pre-clinical data and the right abdominal anatomy, physiology and biology of ovarian cancer have suggested that understanding, abdominal local cytotoxic drug treatment for ovarian cancer is very reasonable. Intraperitoneal chemotherapy Phase I clinical trial confirmed the chemotherapy drugs and intraperitoneal chemotherapy safety of the technology itself, confirmed the intraperitoneal chemotherapy in the pharmacokinetic advantages.

In some multi-center Phase II clinical trials, surgical results confirmed that about 20% to 40% of second-tier category to cisplatin-based chemotherapy in patients with celiac complete remission, the part of the residual cancer patients <0.5 cm before  acceptable to platinum-based chemotherapy effective systemic System .

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Clinical manifestations of ovarian cancer

Ovarian cancer
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Ovarian cancer difficult and Countermeasures

Ovarian cancer
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Summary of ovarian cancer

Epithelial ovarian cancer in the United States is a relatively rare in Gynecologic Oncology, 2004, there were approximately 25,580 cases of new onset patients, 16,090 cases patients died. The majority of patients with advanced cancer, treatment for surgical resection and postoperative to platinum-based chemotherapy. During the past 10 years, chemotherapy improved survival rates improve, and recurrent tumor treatment more effective. In addition, the genetic risk factors for making in-depth understanding of the prevention strategy to become individualized approach to bilateral tubal women - ovarian surgery. This report summarized the clinical characteristics of epithelial ovarian, after reports focus on the treatment of the latest developments.

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Disseminated and metastasis

1). Transfer of malignant ovarian tumor growth and metastasis, and other parts of the same direct spread of cancer, and the lymphatic and blood way. But the transfer spread mainly by direct more directly transferred to pots, abdominal organs and organizations, or transfer of Tai omentum, mesenteric, in a number of intraperitoneal nodular mass, a certain degree of mobility; Peritoneal or transferred to the pelvic floor in the vaginal fornix after palpation, palpable in the womb may have rectal Waterloo a papillary protrusions, even penetrating pelvic viscera, a sinus, and the rectum,; a vaginal or urethral cancer tissue from the pus and bleeding. Ovarian cancer found in the lymph node metastasis rate as high as 50%, or even transferred to the left supraclavicular lymph nodes, or perineum, is in the diagnosis and treatment of ovarian cancer, attention.

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Premature ovarian function and the relationship between amenorrhea

Amenorrhea is common clinical symptoms, their causes are complex, the causes can be divided into the central nervous system and the hypothalamus, pituitary, ovary and uterus of amenorrhea, including congenital Gonadal Dysgenesis and autoimmune ovarian inflammation. As such closure gonadotropin levels often associated with higher estrogen levels decrease, it said hypergonadotropic amenorrhea, gonadotropin levels higher than normal cycle or reached menopause, clinical manifestations of primary or secondary amenorrhea.

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Ovarian cancer care

One, paclitaxel and cisplatin in the treatment of advanced ovarian cancer care <BR> <BR> 1990s Taxol is more of the treatment of advanced ovarian cancer drug effective, and its unique mechanism is a new type of anti-tubulin role of antitumor drugs. Cisplatin for inorganic platinum metal complex, the cell cycle-specific drug, can inhibit DNA synthesis, combined with their synergies to enhance the effectiveness of [1]. In Division I from July 1996 to July 1998 to 15 cases of advanced ovarian cancer patients with Taxol and cisplatin in the treatment of satisfactory results.

One, information and Methods

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