OVARIAN CANCER

Epithelial ovarian cancer in the United States is a relatively rare in Gynecologic Oncology, 2004, there were approximately 25,580 cases of new onset patients, 16,090 cases patients died. The majority of patients with advanced cancer, treatment for surgical resection and postoperative to platinum-based chemotherapy. During the past 10 years, chemotherapy improved survival rates improve, and recurrent tumor treatment more effective. In addition, the genetic risk factors for making in-depth understanding of the prevention strategy to become individualized approach to bilateral tubal women - ovarian surgery. This report summarized the clinical characteristics of epithelial ovarian, after reports focus on the treatment of the latest developments.

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I. Overview

With the aging of the global trend of development, improve the economic status of women, more and more women start hormone replacement therapy (Hormone Replacement Therapy, HRT), to improve access to after menopause due to the decrease in the level of sex hormones related to various diseases. Clear evidence that: postmenopausal women with age, the incidence of coronary heart disease increased by about four times the fracture due to osteoporosis by 20%, died of complications due to pelvic fracture rate of 30%, after the 65-year-old Alzheimer's incidence rate increase every year <BR> and Application HRT can peer groups coronary heart disease risk 50% Alzheimer's risk reduced three times, especially worth mentioning is significantly reduced the incidence of rectal cancer. Long-term use of HRT cancer risk reduced year by year. HRT can also greatly improve the menopause, postmenopausal women with disease or ovarian surgery, radiotherapy in patients with a series of artificial menopause syndrome.

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Swedish experts recently warned that, for those with breast or ovarian cancer family history of the young women, if they have been diagnosed with breast cancer, then their risk of ovarian cancer risk would be significantly increased by 10 times. So even the experts recommended that certain breast cancer patients may be necessary for the prevention of suffering from such as ovarian cancer
Preventive measures. Kjell Bergfeldt Karolinska Institute, Doctor of Medicine, in its study of more than 30,000 cases compared 70 patients with breast cancer under the age of the medical records, and also whether their immediate family members with breast cancer or ovarian cancer cases were investigated. The results showed that if their mothers, sisters or daughters of people with breast cancer or ovarian cancer, who before the age of 40 was diagnosed with breast cancer before the age of 70 women with ovarian cancer risk will increase six-fold and 17-fold. Relevant experts believe that the discovery confirmed the existence of two types of cancer among some related links. Previous studies have already noted, carrying the BRCA1 or BRCA2 gene mutations in breast cancer patients with about 40% of people will be suffering from ovarian cancer.

Tags: age, brca1, breast, cancer, cases, ert, family, gene, history, increased, mutation, ovarian, patients, preventive, risk, study, time, women

【Medical industry network was HealthScoutNews August 28, 2002 - 40 years before being diagnosed with breast cancer in women if the family history of cancer or ovarian cancer, with more risk of ovarian cancer than those without family history. Sweden also show that the conclusion of the study: high-risk women should closely follow-up counseling, and to consider the removal of ovarian prevention. See today's "Lancet" (The Lancet) magazine Web content.

Tags: age, brca1, breast, cancer, cause, children, diagnosis, early, ert, family, gene, history, increased, method, mutation, ovarian, patients, preventive, risk, study, time, women