OVARIAN CANCER

The clinical diagnosis of ovarian tumors should meet four requirements:
(1) whether ovarian tumor;
(2) what ovarian tumor;
(3) Whether complications;
(4), Mr lateral growth.

Regarding the diagnosis of ovarian tumors
Ovarian cancer diagnosis often tumor size, different characters with ease and the difference, when asked in detail about history not only to genital mutilation, and the situation required attention to the whole body and other vital organs of the relevant history; Combined with clinical manifestations and physical examination, in addition to the characteristics of tumor itself, the whole body should be aware of the situation yet , it not only gynecological examination, and whole body check, especially abdominal inspection also very important. When necessary, with other diagnostic methods, such as pregnancy tests, the whole digestive tract X-ray fluoroscopy, hysterosalpingography, intravenous pyelography, diagnostic ultrasound or CT, MRI, and the special circumstances of individual abdominal puncture, laparoscopy, laparotomy, combined with the history after a comprehensive analysis in order to get a correct diagnosis.

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Ovarian cancer is the female reproductive system cancer one of the three, as misprision of clinical symptoms, the lack of an effective method for early diagnosis, over 80% of patients had treatment for late mortality gynecologic malignancies in the first place. CA-125 tumor marker specificity is not strong, there false positive, we can not separate screening for ovarian cancer. High-throughput protein groups for the study of information technology and biological tools for ovarian cancer biomarkers of mass rapid screening provided a powerful weapon.

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Because some patients with abdominal mass for the first symptom, the disease easily confused with primary ovarian cancer. While most patients with muscle. Therefore, the CT-assisted examination found pelvic masses accurate diagnosis difficult and the nature of its sources. Shoji Kamiura reported in 64 patients, only 50% of patients (19/38) in the initial treatment has been confirmed by histopathology metastatic ovarian cancer, and in these 19 patients, only 37% (7 / 19) in the preoperative diagnosis, and the rest 63% (12/19) is OK pathological examination after diagnosis.
In recent years, CEA monoclonal antibody research in the identification of primary and metastatic ovarian cancer provided some evidence. But CEA in primary ovarian cancer in a certain expression.且CEA种类繁多，因此需要找到一个有效的CEA单克隆抗体来鉴别原发灶或转移性卵巢癌，CA125为卵巢癌单抗，在浆液性卵巢癌中表达率最高，而在粘液性卵巢癌中阴性，故CA125在鉴别诊断中有一定限制。 Thomas Rutherford, reported that their research shows that in metastatic ovarian cancer, the lack of ER - β expression. China's Fudan University, Shanghai Medical College Cancer Hospital study found: cytokeratin 7 monoclonal antibodies in the primary ovarian carcinoma in pursuing expression in gastrointestinal adenocarcinoma sources of generally negative.

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" Cancer, "a magazine published care Ovarian cancer.

A total of 80,326 women aged 30-55 who participated in the study began in 1976. Subjects in 1980,1984,1986 and 1990 to complete the consumption frequency of the survey questionnaire. In more than 16 years of follow-up period in subjects with 527 cases of ovarian cancer.

Boston, Harvard University Kathleen M. Fairfield School of Medicine and colleagues, multivariate analysis showed that: intake of vitamin A, vitamin C or beta-carotene and the risk of ovarian cancer unrelated.

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One, paclitaxel and cisplatin in the treatment of advanced ovarian cancer care <BR> <BR> 1990s Taxol is more of the treatment of advanced ovarian cancer drug effective, and its unique mechanism is a new type of anti-tubulin role of antitumor drugs. Cisplatin for inorganic platinum metal complex, the cell cycle-specific drug, can inhibit DNA synthesis, combined with their synergies to enhance the effectiveness of [1]. In Division I from July 1996 to July 1998 to 15 cases of advanced ovarian cancer patients with Taxol and cisplatin in the treatment of satisfactory results.

One, information and Methods

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Clinical manifestations

(1) a <BR> symptoms, age occurred in perimenopausal women. Over more than 35 years of epithelial ovarian cancer, while those below the age of 35 occurred reproductive cell malignancies.
2, the pain may be due to malignant ovarian tumor of the changes, such as hemorrhage, necrosis, the rapid growth caused a considerable degree of persistent pain. The inspection found a local tenderness.
3, Irregular Menstruation see irregular bleeding, bleeding after menopause.
4, weight loss was sexually advanced thin.

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The cytological diagnosis of ovarian cancer cells, including shedding diagnosis and fine-needle aspiration cytology diagnosis learned of two parts. Check for gynecologic cytology clinical has for decades. Fine needle aspiration cytology lessons, the past 20 years in various tumor diagnosis has been widely used, this method of diagnosis of ovarian tumors of some value, advanced or recurrent tumors and lymph node metastases diagnosis, not only diagnosis, but also avoid some unnecessary laparotomy.

One, cytological diagnosis

(1) cytology examination: exfoliated cells can be obtained specimens from three aspects, including: ① vaginal, cervical and uterine tube; ② ascites or peritoneal fluid; ③ rectal deciduous uterine puncture lessons.

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Ovarian cancer _
(1) due to early diagnosis of ovarian cancer early without typical symptoms and signs, they asked in detail about history and serious medical and gynecological examinations are extremely important. Suspicious circumstances of the event should help of modern imaging examination and generalized tumor marker of early detection screening. The so-called suspicious circumstances may be more long ovarian dysfunction, long unexplained gastrointestinal or urinary tract symptoms, or young girls increased postmenopausal ovarian hit ovarian, and the original suspected ovarian tumor rapidly increasing fixed, stiffen, and so on.

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In Orlando at the American Association for Cancer Research annual meeting, Philadelphia's Fox Chase Cancer Center researchers proposed a new research results, analgesic drugs such as aspirin, ibuprofen, Celebrex and Vioxx could help prevent ovarian cancer, these common anti-inflammatory drugs could inhibit cox 2 enzyme, may be able to slow the rapid ovarian cell changes, and can reduce the formation of malignant cells potential risks.

The study leader Xiang-Xi (Mike) Xu said that the cox-2 enzyme have a role in the process is unusual mechanism. When we released the report, it is obvious that this truth, but before this mechanism was not found.

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(1). Complete removal of lesions in ovarian cancer surgery should be the primary tumor resection can see pots and peritoneal metastasis, or to residual tumor diameter is less than 2.0 to 1.5 cm. The epithelial cancer, but also for greater omentum and appendectomy.

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