OVARIAN CANCER

Amenorrhea is common clinical symptoms, their causes are complex, the causes can be divided into the central nervous system and the hypothalamus, pituitary, ovary and uterus of amenorrhea, including congenital Gonadal Dysgenesis and autoimmune ovarian inflammation. As such closure gonadotropin levels often associated with higher estrogen levels decrease, it said hypergonadotropic amenorrhea, gonadotropin levels higher than normal cycle or reached menopause, clinical manifestations of primary or secondary amenorrhea.

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One, paclitaxel and cisplatin in the treatment of advanced ovarian cancer care <BR> <BR> 1990s Taxol is more of the treatment of advanced ovarian cancer drug effective, and its unique mechanism is a new type of anti-tubulin role of antitumor drugs. Cisplatin for inorganic platinum metal complex, the cell cycle-specific drug, can inhibit DNA synthesis, combined with their synergies to enhance the effectiveness of [1]. In Division I from July 1996 to July 1998 to 15 cases of advanced ovarian cancer patients with Taxol and cisplatin in the treatment of satisfactory results.

One, information and Methods

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Cytoreductive surgery in the treatment of ovarian cancer Comprehensive Application and prospects

Foreign Medical Obstetrics and Gynecology volumes in 1999 Vol 26 No. 2

Tianjin Medical University General Hospital of Obstetrics and Gynecology (300,052) of the new QU (Summary) if Mi (revision)

Abstract <BR> since the 1980s, complete cytoreductive surgery to cisplatin-based combination chemotherapy for ovarian cancer as a conventional model, cytoreductive surgery is the complete impact of the prognosis of patients with one of the important factors for recurrent ovarian cancer once again cytoreductive surgery still some value , but to improve the survival rate of patients is more important to be effective after chemotherapy treatment as a necessary complement. Early ovarian cancer retroperitoneal lymph node dissection is reasonable and significance of the still controversial.

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Diagnosis
Not obvious early symptoms of ovarian cancer, so early diagnosis depends on the regular census.

1. Past history should be asked whether particular pelvic mass or the recent history of tumor growth. Women over 40 years of age and unexplained gastrointestinal symptoms, and should be gynecological examinations.
2. Body check, can be found abdominal mass, ascites positive sign.
3. Gynecological examinations beside mass, although it is solid or cystic, irregular activities of the poor, and often bilateral. Triple consultation found dome nodule or mass.
4. Auxiliary

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Mesenchymal cells of the ovary (Loydig cell tumor):

(1) of the cell door: This tumor is rare. As a <BR> ovarian portal that since the tumor cell door. More common in women after menopause, the main clinical manifestations of masculine symptoms, but sometimes there will be high performance estrogen, and with endometrial hyperplasia, endometrial cancer.

[Giant seizure] often unilateral, bilateral and occasionally simultaneously ovarian tumor. Tumor sizes. In ovarian portal, but the majority of ovarian tumors can be occupied. Tumor section for substantive, yellow or brownish yellow, with cystic degeneration and bleeding.

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Ovarian cancer is common gynecologic cancer, female genital tumors about 1 / 3. Can occur at any age, and women with reproductive seen. The incidence of ovarian cancer is women's genital cancer Habitat third place, as early diagnosis difficult, often found at the already advanced, but the mortality rate for the first gynecologic malignancies.
[Diagnosis]

A Symptoms

(1) abdominal discomfort or medium sized benign tumor rapid growth often cause bloating and discomfort.

(2) abdominal mass benign swelling growth slow, difficult to be discovered, patients are often inadvertently touched. Malignant tumors grow fast, easily detected.

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Ovarian cancer mortality first Habitat gynecologic malignancies, as misprision of onset, 70% of patients when treatment is already advanced. Surgery and chemotherapy comprehensive application is the treatment of advanced ovarian cancer, especially epithelial ovarian cancer therapy of choice. Platinum drug resistance ovarian cancer is the main reason for treatment failure. To solve this problem, clinical oncologist to a variety of solutions, is chosen in 2003 after the open literature on the following:

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[Summary]

Ovarian cancer is a common cancer of female genital mutilation one of the incidence of cervical cancer and after cancer of the uterus, which ranked third. But ovarian cancer death, accounts of the first gynecologic tumors, right pose a serious threat to women's lives. Because ovarian embryonic development, organization anatomy and endocrine function more complicated, it may be suffering from benign tumors or malignant. Because of early ovarian cancer in asymptomatic, and the identification of its type benign and malignant very difficult, ovarian carcinoma laparotomy in ovarian tumor confined to only 30%, most have spread to the uterus, bilateral annex, the omentum and pelvic organs, both in the diagnosis of ovarian cancer and governance the treatment is a major problem indeed. Over the years experts on the pathological form of ovarian cancer, the development of clinical and treatment programs for many of accumulated a lot of experience, so far, statistics on domestic and foreign clinical data, the five-year survival rate of only 25% to 30%.

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The choice of ovarian cancer surgery, chemotherapy and radiotherapy. But because of its pathological type complex, qualitative, without a diagnosis and staging laparoscopy or laparotomy, it is difficult clear. In addition to surgery is not generally the case or have the type of tumor in patients with systemic conditions not competent to surgery, chemotherapy or radiotherapy to trial again after surgery to consider, as appropriate, generally the preferred treatment. Surgical exploration can be further defined tumor types and scope of involvement, clear staging, not only for postoperative chemotherapy and radiotherapy provide basis, and possible removal of the tumor, chemotherapy or postoperative radiotherapy or create conditions to improve efficacy.

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(1) B - ultrasound imaging can detect tumor location, size, shape and nature.

(2) radiology diagnostic barium contrast barium enema or air contrast to know whether gastrointestinal tumors. CT of pelvic tumors can locate and identify and understand the liver, lung and retroperitoneal lymph node metastasis there. Contrast pelvic lymph nodes can be judged without milk ovarian tumor lymphatic metastasis.

(3) laparoscopy can be directly observed tumor sources and generally, and the entire basin and transverse abdominal separated, and to determine the scope of other diseases. Ascites and lessons for cytology, or from dubious organizations for pathological examination. However, the enormous mass or tumor adhesion taboo.

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