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According to a South African study shows that the abnormal heart check found after a high cost screening, cervical cancer screening more patients. The researchers found that this two-stage screening can significantly reduce those were classified as abnormal disease is not found and the number of women, so that they avoid unnecessary treatment.
In assessing the screening methods, Columbia University, New York Medical College surgical Thomas C. Wright, Jr.. And colleagues on 1,335 women conducted four inspections, including: heart examination, human papillomavirus (HPV) DNA test, cervical cytology and angiography.
It was published in the August edition of the American Journal of Obstetrics and Gynecology on an article reported that the four methods in every 1,000 women check out 24, 26, 2007-09-07 16:00:00 and 2007-09-07 16:00:00 cases of highly squamous intraepithelial lesions or cancer. This method of false positive results for every 1,000 women in the 182, 71, 137 and 112 cases.
Dr. Wright and his colleagues expected, after two stage screening, or abnormal heart check then found HPV screening, cervical cytology or angiography, which would reduce the initial seizure recognized as abnormal number of women. Researchers calculated the screening method in every 1,000 women diagnosed with 16 to 18 cases.
Dr. Wright told reporters that "the idea of the screening method is preceded by the relatively high sensitivity and specificity of screening lower again on the first positive results of the inspections have been carried out another inspection of women to improve specificity."
Researchers explain how this model can be expensive than using only a single method identified more patients. For example, if 1,000 women inspection PAP smears, measured about 26 patients. However, if open to inspection as early seized, and then the positive results for PAP smears, which were equivalent to 4,854 the number of women simply PAP smears and the detection of patients with this two-stage screening method detected 89 patients.
Dr. Wright noted that in the absence of the conditions for cytology, HPV screening may be more effective. "The most sensitive screening method is open and HPV screening. In developing countries, PAP smears and HPV screening is spent. "
The researchers concluded that, in resource poor areas of the two-stage screening will be fewer women in poor prognosis and higher cost of treatment.
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