Ovarian cancer treatment
A benign ovarian tumors young patients affected Annex tumor resection or stripped of. If both bilateral ovarian tumors, should fight to retain part of normal ovarian tissue. Before post-clearance as abdominal specimens suspected malignant sent frozen biopsy. Patients before and after menopause to be hysterectomy and bilateral resection of the Annex to activities.
2, malignant ovarian tumor treatment to the main, supplemented by chemotherapy, and radiotherapy.
(1) to general surgery for hysterectomy, bilateral Annex and the omentum resection. Patients with advanced cancer should be possible for the transfer to that reduction of tumor cells. As for retroperitoneal lymph node removal of the therapeutic value can not be determined.
(2) Chemical treatment for the major complementary therapies. Estimated surgical removal of the tumor difficulties, first with a preoperative treatment to two chemotherapy can improve surgical resection. After application of chemotherapy can prevent recurrence; Surgical excision is not complete, after chemotherapy will be temporarily alleviate or even long-term survival; Surgical resection can not, chemotherapy can reduce tumor loose, creating conditions for reoperation.
On the choice of chemotherapy drugs, dosage, route and course of treatment has not yet been unified. The effect of large-dose intermittent use smaller doses than continuing medication, chemotherapy combination chemotherapy is better than single by histologic classification developed better chemotherapy:
① systemic chemotherapy to intravenous drug oriented. The current rule Wen epithelial ovarian cancer, use of cisplatin (DDP) and Adriamycin (ADM), Liujia Agent (HMM), cyclophosphamide (CTX), 5 - fluorouracil (5-FU) combined with chemotherapy.
Single-dose cisplatin intravenously general, doxorubicin 30 mg / m2, Liujia Agent 150 mg / m2 (oral), cyclophosphamide 150 mg / m2, 5 - fluorouracil moderate.
Germ cell ovarian tumors, usually VAC program, vincristine (VCR) 2mg, intravenous week a total of 12 times; - Actinomycin D (KSM) 400 μ g, 2 to 6 days infusion; Cyclophosphamide (CTX) 400mg, two to six days injection . In recent years by VAC program at the same time with DDP20mg / m m2, 1 to 5 days infusion, spacing 3 to 4 weeks to repeat. Stromal Tumors of the cable used AFC programs - and actinomycin D0.01/kg daily infusion of a total of five times (the most significant 0.5 mg / d); 5 - fluorouracil moderate daily infusion of a total of five times; Cyclophosphamide balls / kg bolus a daily total of five times. Repeat every four weeks.
② intraperitoneal chemotherapy may direct role in the tumor, high local concentration, excellent exploration results of ascites, less side effects. The current use of 60 ~ 80 mg cisplatin plus saline 1000ml, intravenous hydration, the 24-hour urine volume of 2000ml more, in order to reduce kidney toxicity.
③ arterial injection chemotherapy in under local anesthesia, percutaneous femoral artery, retrograde intubation into the iliac artery injection of anti-cancer drugs, anti-cancer drugs can be reduced and the plasma protein binding, and increase the concentration of free drug; Anti-cancer drugs can increase the cytotoxicity, thereby enhancing effect. In addition, fair reduce systemic side effects.
④ chemotherapy embolization at the same time to arterial infusion of anti-cancer drugs and embolization to the role of the cancer anticancer drugs hypoxia ischemia, necrosis easier.
(3) treatment Xie Fang different types of ovarian cancer, the sensitivity of the different radiotherapy, radiotherapy Dysgerminoma the most sensitive and moderately sensitive granulosa cell tumors, epithelial tumors have certain sensitivity; Postoperative irradiation in vitro against major abdominal pots residual tumor. No intraperitoneal adhesions are minimal residual tumor, in seven to 14 days after reperfusion radionuclides used 32P10 ~ 15mCi, home 300 ~ 500ml saline, slow intraperitoneal injection.
4, Chinese medicine treatment can be used as anti-cancer treatment one of the measures to apply to some not suitable for surgery and radiotherapy or chemotherapy after surgery in patients with relapse.
Tags: abdominal, age, annex, anti, benign, cancer, cell, cells, chemotherapy, cisplatin, days, dose, drug, drugs, eat, ert, exploration, gene, grams, infusion, injection, intraperitoneal, intravenous, irradiation, lymph, malignant, node, ovarian, patients, protein, radiation, radiotherapy, rate, reduce, resection, residual, surgery, surgical, survival, therapy, time, toxicity, treatment, tumor, tumors, usually