Epithelial ovarian cancer proven mechanism
Pain medicine to help prevent ovarian cancer In Orlando at the American Association for Cancer Research annual meeting, Philadelphia's Fox Chase Cancer Center researchers proposed a...
Previous accept carboplatin multidrug chemotherapy in patients with recurrent ovarian cancer Carboplatin and Paclitaxel weekly therapy is safe and effective Kikuchi, the Japanese report, have received platinum multidrug chemotherapy for recurrent ovarian cancer Japanese women, a weekly carboplati...
Henan Medical University, a professor of obstetrics and gynecology buildings Qiao Yu, graduate students and others Rui - Xia Guo recent study found that in some tumor suppressor gene amplification or overexpression of ovarian cancer is the key factor. Entitled "epithelial ovarian cancer tumor mechanism and clinical application of" scientific research, recently Henan "progress of science and technology second prize."
Ovarian cancer is a common malignancy of the female, 5-year survival rate only 25%. The main reason is the incidence of occult comparison, the incidence of early indications of a lack of specificity. Recent studies suggest that ovarian epithelial cell proliferation in ovarian cancer is the most early changes. Qiao Yu, professor of immunohistochemical technique ABC, 35 cases of normal ovarian tissue, 21 cases cystadenoma, 40 patients with epithelial ovarian cancer and 19 patients with metastatic lesions corresponding omentum organizations such as maspin in the tumor suppressor gene, p53 and tumor metastasis suppressor gene in ovarian cancer nm2007-09-07 16:00:00 changes in the process of change the law, and these changes with changes in cell proliferation, such as the proliferation of nuclear antigen (PCNA) relationship. The results showed that: from normal ovarian adenoma to the junction of the ovarian cancer tumor, PCNA labeling index of ovarian cancer with increasing levels increased; Different types of ovarian tissue between maspin expression of the basic agreement, maspin expression in cancer tissues was significantly lower than normal epithelial ovarian, adenoma and borderline tumors maspin rate, and with ovarian cancer increased level of decline; serous ovarian cancer p53 expression was significantly higher than that of mucinous carcinoma and endometrial cancer, ovarian tissue with increased levels of p53 labeling index is gradually increasing; ovarian cancer and its corresponding omentum metastases without the gene expression significant differences.
The above results show that: PCNA to a certain extent, reflect the malignant ovarian cancer, and the right understanding of the development process and its benign and malignant lesions have some value; Maspin ovarian cancer gene is another important process of molecular change, and ovarian cancer differentiation positively correlated; Nm2007-09-07 16:00:00 and ovarian cancer the occur in ovarian cancer cell differentiation process is a regulatory role. the p53 gene mutation in serous ovarian cancer in the development of greater significance, and ovarian cancer histologic grade were positively correlated; p53 and PCNA labeling index is a linear correlation, and nm2007-09-07 16:00:00 and maspin and cell proliferation was negatively correlated.
Beware of genetic factors of ovarian cancer The possible risk of ovarian cancer risk factors, including age, not infertility, diet, ovulation drug therapy. But if family history of br...
Cytoreductive surgery in the treatment of ovarian cancer Comprehensive Application and prospects Cytoreductive surgery in the treatment of ovarian cancer Comprehensive Application and prospects Foreign Medical Obstetrics and Gynecology...
Summary of ovarian cancer Epithelial ovarian cancer in the United States is a relatively rare in Gynecologic Oncology, 2004, there were approximately 25,580 cases of ...
Type Surface epithelial stromal tumor (epithelial ovarian cancer) 1), serous carcinoma (papillary adenocarcinoma and cystic papillary adenocarci...
Ovarian cancer causes which (1) genetic and familial factors. About 20% to 25% of ovarian cancer patients have family history. The so-called familial aggregation of ova...
Ovarian cancer and vascular endothelial growth factor related Fourth Military Medical University Xijing Hospital maternity doctor completed a Biochemistry and the National Natural Science Foundation-fun...
Two new studies provided information on the latest news of ovarian cancer
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