Early ovarian cancer surgical staging important clinical value
Conventional treatment The choice of ovarian cancer surgery, chemotherapy and radiotherapy. But because of its pathological type complex, qualitative, without a di...
Fallopian tube cancer Primary tubal cancer is scarce. This cancer patients, the average age is 50 to 60 years old. Risk factors not yet well defined, however, ch...
A scholar from the Netherlands led multinational collaborative research suggest that the early epithelial ovarian cancer surgical staging, can predict whether the patients have residual ovarian cancer and the need for postoperative adjuvant chemotherapy.
Studies were included from November 1990 to March 2000 to 448 cases with histologically confirmed early (FIGO Ⅱ a) epithelial ovarian cancer patients.在手术切除肿瘤并进行分期后，将病人随机分为观察组（２２４例）及辅助化疗组（２２４例）。 Adjuvant chemotherapy required at least four cycles of cisplatin-containing combination chemotherapy, follow-up time from three months to nine years, with a median period of 5.5 years. In accordance with the strict standards of comprehensive surgical staging and tumor cell type, tumor grade of histological examination. The need to tumor recurrence histology and cytology confirmed. Eventually, only 151 cases (34%) patients with complete surgical staging, with the remaining patients missed at least do a phased steps. Two of the five patients, no significant difference in overall survival (P = 0.10), but the chemotherapy group of 5-year survival rate from 68% to 76%, significantly higher than the observation group. Multivariable analysis showed that satisfaction with surgical staging, tumor grade and tumor cell types (except for mucinous and endometrial carcinoma) on the survival rate with independent forecasts significance. In the observation group, the patients with surgical staging is not satisfied with poor prognosis in patients with stage. But in chemotherapy patients, the prognosis no difference between the two. Observer Group in the surgical staging of patients with survival rates of survival with and without adjuvant chemotherapy group compared with surgical staging with no significant difference. The group of patients with surgical staging is not satisfied with the overall survival and disease-free survival rate was significantly lower than chemotherapy patients dissatisfied with the operation in stages. On the other hand, the observation group in the relapsed patients receiving chemotherapy to save the efficacy of chemotherapy seems to be better than patients with recurrence. The main author of that adjuvant chemotherapy for early ovarian cancer after the remnants of occult lesions effective, its effect on residual ovarian cancer will spread, and surgical staging of satisfaction can be suggested that just the existence of surviving ovarian cancer.
Comments: Some people think of early ovarian cancer do not have to do such a large operation, some basic hospital was not the early stages of ovarian cancer surgery. This Tip: The more early cases, surgical staging the more important; Not yet satisfied with the staging of patients with surgery, chemotherapy must.
Ovarian cancer clinical manifestations and treatment Clinical manifestations (1) a <BR> symptoms, age occurred in perimenopausal women. Over more than 35 years of epithelial ovarian canc...
Model Diagnosis The cytological diagnosis of ovarian cancer cells, including shedding diagnosis and fine-needle aspiration cytology diagnosis learned of two...
Ovarian cancer knowledge Basic symptoms: early ovarian cancer usually no obvious symptoms, if there is non-specific symptoms, such as menstrual disorder, mild gastr...
Diagnosed with ovarian cancer diagnosis Ovarian cancer early detection, early treatment, the greater the chance of cure. But ovarian cancer early detection more difficult. Usually...
Complete remission after isolation of patients with recurrent ovarian cancer viable again cytoreductive surgery Denmark Gronloud such report, as paclitaxel plus platinum chemotherapy after complete remission in patients with ovarian cancer, if recurren...
Diagnostic Classification Surgery According to a medical examination and transvaginal ultrasound findings suspected ovarian cancer is often a laparotomy to be confir...
Cytoreductive surgery in the treatment of ovarian cancer Comprehensive Application and prospects
How to reduce the recurrence of ovarian cancer
Tags: age, cancer, carcinoma, cases, cell, chemotherapy, cisplatin, clinical, early, examination, group, ovarian, patients, poor, prognosis, rate, residual, staging, surgery, surgical, survival, therapy, time, tumor