Cervical cancer virus with head and neck cancer
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Usually that cervical cancer is a certain type of human papilloma virus (HPV) caused. Now Johns Hopkins University researchers think that some head and neck cancer, particularly tongue and tonsil cancer with the following regional HPV infection. They also found that HPV-positive head and neck cancer prognosis, the other with head and neck cancer different.
V. said Dr. Keerti Shah, head and neck cancer usually is not a good prognosis, in the majority of patients the disease is advanced only found. However, HPV-positive cancer under the microscope is obvious characteristics, so pathologists can immediately determine whether the HPV-positive tumors.
In May 3 published in the Journal of the National Cancer Institute, Dr. Shah and his colleagues published their study report. In 253 cases of head and neck cancer patients in the detection of HPV. 25% of the cases of HPV found that 90% of the HPV-positive tumors also a subtype HPV16, which usually subtype and the cervix.
HPV-positive tumors with HPV-negative tumors are obvious differences. On the one hand, there are obvious differences under the microscope, HPV-positive tumors on the other hand very few of the P53 gene mutation. In severe drinkers and smokers, HPV-positive tumors than other types of head and neck tumors less. According to these characteristics, the researchers think this may be the same cancer HPV infection.
In patients with HPV-positive tumors compared with other cancer patients, died of cancer less likely to be 59%. This may be undermining the capacity of HPV as some environmental factors, such as smoking. In addition, HPV-positive tumors more sensitive to radiation.
In a commentary, Harvard University David T. W. Wong and Dr. Karl Munger high-risk HPV-related head and neck cancer may be associated with cervical HPV similar but not equivalent. They believe that this discovery of great value, because it head and neck cancer patients in the diagnosis and treatment are important.
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