Basic knowledge of ovarian cancer pathology
You know how many pairs of ovarian cancer You are interested in the manual open to learning the prevention and treatment of ovarian cancer, you may answer the following questions, wh...
Not all of malignant ovarian tumor With the development of diagnostic techniques, the knowledge of preventing cancer, gynecological work of the census, many ovarian tumors are...
Disease Overview
The incidence of ovarian cancer may have to be second to cervical cancer and cancer of the uterus, or gynecologic malignancies section 3, but because of ovarian tumors deep in the pelvis, the sick little early symptoms, diagnosis, resulting in 60% to 70% of patients with ovarian cancer is already advanced so far with this states have not changed. In recent decades, cervical, uterine carcinoma, and malignant tumors of trophoblast cells significantly increased mortality decreased significantly. Although the present foreign started early diagnosis of ovarian cancer research, and is generally carried out in the comprehensive treatment of surgery, but because of the many pathological classification, structure complex, and all have different biological characteristics, and the chemotherapy, radiotherapy and the sensitivity of different handling of the resulting hardship The impact of hard, it nearly 20 years ago of ovarian cancer survival rate of five still hovering in the lower levels (20% ~ 30%), the mortality rate of more than cervical and uterine cancer and, first of gynecologic tumors. To this end, ovarian cancer causes and preventive measures for early diagnosis, to acquire all types of ovarian cancer biological characteristics, and explore effective combination therapy is to improve the survival rates of ovarian cancer, the key to reducing mortality.
Pathological etiology
Ovarian cancer etiology remains unclear, but the environment and endocrine effects in ovarian cancer risk factors in the most attention, in addition to the regional differences, racial distinction and eating habits and so on. These factors mainly in ovarian cancer incidence in the world the reasons for the disparity between the rate, the highest incidence of Norway (15.3/10) than the lowest incidence of Japan (smear) nearly five times. White incidence of the disease was 12.9/10 10,000, but living in San Francisco Chinese incidence rate 8.5/10 million, representing whites low, but more in Shanghai and Hong Kong 5.0/10 5.8/10 10,000 10,000 high. The Hawaii of Japanese settlers ovarian cancer incidence rate with the continuous residence and the conduct of the increase. Black morbidity (10.3/10 10,000) than whites (13.3/10) low. The upper class women's risk of ovarian cancer than women in the lower social higher.
From the age of onset of ovarian cancer is the most wide Gynecologic Oncology, women can happen at any time in life. Histological different types of ovarian cancer age distribution is very different. Ovarian cancer have early menarche age bias phenomenon before the age of 14 after a 18-year-old high-risk four times, and the age of menopause does not affect the incidence of ovarian cancer, infertility, unmarried and not a high incidence of the control group, the fewer the number of births occurred increase the likelihood of ovarian cancer.
Some may lead to ovarian cancer factors such as X-rays, infection (mumps, flu, etc.), chemical carcinogenesis and factors such as excessive intake of animal fats.
Ovarian cancer histopathological classification
Germinal epithelial tumors
Germinal of epithelial ovarian cancer tumors 2 / 3, mostly from the ovarian surface germinal epithelium. Coverage for germinal epithelial ovarian surface epithelium, it is multi-functional differentiation potential, it can be formed serous tumor, mucinous tumors and endometrial cancer samples.
Of REQUEST - stromal tumor
Of REQUEST - stromal tumors accounted for 6% of ovarian tumors. Most of the functions of the cells of ovarian granulosa cells have, theca cells; Testicular cells to the differentiation of supporting cells, mesenchymal cells. Such tumors are more complicated and can separate the various components of the corresponding tumor, ovarian or testicular type of the two cells appear in the same tumor, four more types of cells in the tumor at the same time see.
Steroid cell tumor (tumor cell lipid)
Steroids by the tumor cells similar to the luteal cells, stromal cells, adrenal cortical cells, large circular or polygonal cells formed tumors. Before that lipid or lipid cells of tumor cells. As part (approximately 40%) within the tumor cells of non-lipid rich, it also called steroid tumor.
Germ cell tumors
Germ cell tumors more common. In North America and Europe after the germinal epithelial tumors, ovarian tumors accounted for 20% of malignant ovarian cancer by 3%. In Asia and Africa, seen more germinal epithelial tumors, malignant, as high as 15%. Germ cell tumors can be found in any age, but see more young people, children and adolescent women, 60% of ovarian germ cell tumor is the source, 1 / 3 malignant.
Germ cells - of the cable stromal tumors
Such tumors are two basic components, namely, sexual and reproductive cells from cord.
Unknown tumor cell types
Mainly small cell ovarian cancer, liver cancer and the like may Wolff sources tumors.
Sources mesenchymal tumors
Fibroids are the most common tumors of mesenchymal origin, followed by leiomyoma, hemangioma, is the rare neurogenic tumors, lipoma, lymphangioma, chondroma, osteoma. Have occurred recently in the door of the adenoma ovarian tumor coverage.
Metastatic cancer
Ovarian cancer is common sites of metastases, about 10% of metastatic ovarian cancer is the most common from the gastrointestinal tract, breast and reproductive tract of metastatic carcinoma.
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